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Index > Protein center > RGS10(Gene name) > Human
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  • RGS10 (Gene name),
  • Regulator of G-protein signaling 10 (Protein name ),  RGS10_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    RGS10;
    Protein name:
    Regulator of G-protein signaling 10(RGS10);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)-alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity on G(z)-alpha is inhibited by palmitoylation of the G-protein.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    173
    Sequence:
    50:
    MQSELCFADI | HDSDGSSSSS | HQSLKSTAKW | AASLENLLED | PEGVKRFREF | 
    100:
    LKKEFSEENV | LFWLACEDFK | KMQDKTQMQE | KAKEIYMTFL | SSKASSQVNV | 
    150:
    EGQSRLNEKI | LEEPHPLMFQ | KLQDQIFNLM | KYDSYSRFLK | SDLFLKHKRT | 
    173:
    EEEEEDLPDA | QTAAKRASRI | YNT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    String:
    MIM:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human RGS10
    Cat.:
    E0250h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human RGS10
    Cat.:
    E0250r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human RGS10
    Cat.:
    E0250m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human RGS10
    Cat.:
    E0250b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human RGS10
    Cat.:
    U0250h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human RGS10
    Cat.:
    U0250b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human RGS10
    Cat.:
    U0250r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human RGS10
    Cat.:
    U0250m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human RGS10
    Polyclonal Antibody for Human RGS10
    Cat.:
    P0250Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human RGS10
    Cat.:
    P0250Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human RGS10
    Cat.:
    P0250Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human RGS10
    Monoclonal Antibody for Human RGS10
    Monoclonal Antibody for Human RGS10
    Monoclonal Antibody for Human RGS10
    Protein for Human RGS10
    Protein for Human RGS10
    Protein for Human RGS10
    Protein for Human RGS10

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    References
    1. 1.
      "RGS10 is a selective activator of G alpha i GTPase activity."
      Hunt T.W. , Fields T.A. , Casey P.J. , Peralta E.G.
      Nature383:175-177(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Cytoplasmic, nuclear, and Golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifs."
      Chatterjee T.K. , Fisher R.A.
      J. Biol. Chem.275:24013-24021(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    3. 3.
      "Phosphorylation and nuclear translocation of a regulator of G protein signaling (RGS10)."
      Burgon P.G. , Lee W.L. , Nixon A.B. , Peralta E.G. , Casey P.J.
      J. Biol. Chem.276:32828-32834(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    4. 4.
      "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Puhl H.L. III , Ikeda S.R. , Aronstam R.S.
      Submitted (2002-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
    6. 6.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    7. 7.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Uterus.
    10. 10.
      "Palmitoylation of a conserved cysteine in the regulator of G protein signaling (RGS) domain modulates the GTPase-activating activity of RGS4 and RGS10."
      Tu Y. , Popov S. , Slaughter C. , Ross E.M.
      J. Biol. Chem.274:38260-38267(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-66
    11. 11.
      "Inhibition of brain Gz GAP and other RGS proteins by palmitoylation of G protein alpha subunits."
      Tu Y. , Wang J. , Ross E.M.
      Science278:1132-1135(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INHIBITION
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Solution structure of the RGS domain of human regulator of G-protein signaling 10."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2006-10) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 23-158
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